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AKTU Bioprocess Engineering (BBI062) Syllabus PDF – B.Tech 3rd Year
Bioprocess Engineering BBI062
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Official AKTU syllabus of Bioprocess Engineering (BBI062) for B.Tech 3rd Year – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Bioprocess Engineering
Download PDFBBI062 · 3 credits · L-T-P 3-0-0
Course Outcomes
At the end of the course, the student will be able to:
| CO1 | Explain the principles of bioprocess engineering, microbial growth, and fermentation systems. | K2 |
| CO2 | Apply bioreactor design concepts and scale-up criteria for industrial bioprocesses. | K3 |
| CO3 | Explain mixing, mass transfer, and oxygen transfer phenomena in bioreactors. | K2 |
| CO4 | Apply sterilization methods, strain improvement techniques, and media formulation strategies in fermentation processes. | K3 |
| CO5 | Explain immobilized cell systems and proteomic techniques for modern bioprocess and biotechnology applications. | K2 |
Course Content
L-T-P: 3-0-0
| Unit | Topic | Proposed Lecture |
|---|---|---|
| I | INTRODUCTION: Introduction to Bioprocess, Microbial process development, Fermentation Economics, Batch culture, Continuous culture, kinetics, Chemostat with recycle and multistage Chemostat Systems. Modify batch reactors: Fed-batch operation, Perfusion systems. | 08 |
| II | BIOREACTOR DESIGN SCALE UP, SCALE DOWN: Bioreactor configurations, Analysis of ideal and non-ideal reactors. Multiphase reactors: packed-bed reactors, bubble-column bioreactors, fluidized bed bioreactors, trickle-bed reactors. Bioprocess Considerations: Animal cell cultures & plant cell cultures Scale up of bioprocesses-based on oxygen transfer, power consumption and impeller tip speed, Scale down. | 09 |
| III | MIXING & MASS TRANSFER: Mixing equipments, flow patterns in reactors, mixing mechanism, power consumption and shear properties of sparged and agitated vessels and various mixing agitators. Diffusion, mass transfer, Oxygen transfer in fermenters. | 08 |
| IV | STERILIZATION, STRAIN IMPROVEMENT AND MEDIA FORMULATION: Design of batch and continuous sterilization processes, kinetics of thermal death of cells and spores. Strain improvement of industrially important microorganisms, Media formulation industrial fermentations. | 08 |
| V | IMMOBILIZED CELL SYSTEMS (ICS): Mass Analysis-Tandem Mass Spectrometry (MS/MS)-Ion Detectors-Ionization of the Sample. Sample Preparation/Analysis-Proteins and Peptides- Protein Folding. | 07 |
Text Books
- Pauline M. Doran, “Bioprocess Engineering Principles”, 8th ed., Academic Press, New York, 2003.
- M.L. Shuler and F. Kargi, “Bioprocess Engineering--basic Concepts”, 2nd Edn., Prentice-Hall Of India Pvt Ltd (2008).
- Peter F. Stanbury, Stephen J. Hall & A. Whitaker, “Principles of Fermentation Technology”, Elsevier India Pvt Ltd. (2007).
- Klaas Van’t Riet, Johannes Tramper, “Basic Bioreactor Design”, 2nd ed., Marcel Dekker, Inc., New York, 1991.
- Bailey and Ollis, “Biochemical Engineering Fundamentals”, 2nd ed., McGraw- Hill Book Company, New York, 1986.
- Mccabe L. Warren, Smith C. Julian and Peter Harriott, “Unit Operations of Chemical Engineering”, 6th ed., McGraw Hill International Edition, New York, 2001.
- Abhilasha S. Mathuriya, “Industrial Biotechnology”, 1st ed., Ane Books Pvt. Ltd., New Delhi, 2009.
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