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AKTU Pharmacogenomics & Pharmacogenetics (BBI057) Syllabus PDF – B.Tech 3rd Year

Pharmacogenomics & Pharmacogenetics BBI057

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  • Semester 5
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Official AKTU syllabus of Pharmacogenomics & Pharmacogenetics (BBI057) for B.Tech 3rd Year – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.

Syllabus — Pharmacogenomics & Pharmacogenetics

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BBI057 · 3 credits · L-T-P 3-0-0

Course Outcomes

At the end of the course, the student will be able to:

CO1Understand historical aspects of pharmacogenetics, pharmacogenomics, biomarkers, and personalized medicine.K2
CO2Apply knowledge of pharmacogenetics in drug metabolism, receptors, and transporters.K3
CO3Explain inter-ethnic drug responses, clinical viewpoints, and related technologies.K2
CO4Explain single nucleotide polymorphisms (SNPs) and technologies for molecular diagnostics.K2
CO5Explain Serial Analysis of Gene Expression (SAGE) for functional biology and disease mapping.K2

Course Content

L-T-P: 3-0-0

UnitTopicProposed Lecture
IINTRODUCTION: Historical aspects of Pharmacogenetics- Pharmacogenomics- Biomarkers- and the promise of personalized medicine.08
IIPHARMACOGENETICS: Pharmacogenetics of drug metabolism-receptors- drug transporters.08
IIIDRUG RESPONSE: Inter ethnic drug response- clinical viewpoints- technologies and challenges.08
IVSINGLE NUCLEOTIDE POLYMORPHISM: Introduction-technologies for the analysis of SNPs- molecular diagnostics.08
VSAGE: Serial Analysis of Gene Expression (SAGE) - Principle and methodology of SAGE; applications in functional biology; use of SAGE data for mapping of disease loci.08

Text Books

  1. Licinio J. Ma-Li Wong, “Pharmacogenomics: The Search for Individualized Therapies”, Wiley-VCH, 2002.
  2. Zdanowicz M, “Concepts in Pharmacogenomics”, ASHP, 2010.
  3. Werner Kalow, Rachel F Tyndale, Urs A Meyer, “Pharmacogenomics”, Marcel Dekker Inc., 2001.
  4. Adam Hedgecoe, “The Politics of Personalized Medicine- Pharmacogenetics in the Clinic”, Cambridge University Press, first edition, 2004.

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