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AKTU Cancer Biology (BBI058) Syllabus PDF – B.Tech 3rd Year
Cancer Biology BBI058
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Official AKTU syllabus of Cancer Biology (BBI058) for B.Tech 3rd Year – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Cancer Biology
Download PDFBBI058 · 3 credits · L-T-P 3-0-0
Course Outcomes
At the end of the course, the student will be able to:
| CO1 | Understand fundamentals of cancer biology including cell cycle regulation, mutations, tumour suppressor genes, and cancer types. | K2 |
| CO2 | Apply principles of carcinogenesis (chemical, physical, radiation mechanisms). | K3 |
| CO3 | Explain molecular cell biology of cancer focusing on oncogenes, growth factors, and transformations. | K2 |
| CO4 | Explain principles of cancer metastasis including invasion, heterogeneity, and the metastatic cascade. | K2 |
| CO5 | Describe new molecules and therapies for cancer, including chemotherapy, radiation, bioinformatics, and advances in detection and AI integration. | K2 |
Course Content
L-T-P: 3-0-0
| Unit | Topic | Proposed Lecture |
|---|---|---|
| I | FUNDAMENTALS OF CANCER BIOLOGY: Regulation of Cell cycle- Mutations that cause changes in signal molecules- effects on receptor- signal switches tumour suppressor genes- Modulation of cell cycle-in cancer- Different forms of cancers- Diet and cancer. | 08 |
| II | PRINCIPLES OF CARCINOGENESIS: Chemical Carcinogenesis- Metabolism of Carcinogenesis- Natural History of Carcinogenesis- Targets of Chemical Carcinogenesis- Principles of Physical Carcinogenesis- X-Ray radiation - Mechanism of radiation Carcinogenesis. | 08 |
| III | PRINCIPLES OF MOLECULAR CELL BIOLOGY OF CANCER: Oncogenes- Identification of Oncogenes- Retroviruses and Oncogenes- detection of Oncogenes- Growth factor and Growth factor receptors that are Oncogenes- Oncogenes/ Proto Oncogenes activity- Growth factors related to transformations. | 08 |
| IV | PRINCIPLES OF CANCER METASTASIS: Clinical significances of invasion- heterogeneity of metastatic phenotype- Metastatic cascade- Basement membrane disruption- Three step theory of invasion- Proteinases and tumour cell invasion. | 08 |
| V | NEW MOLECULES FOR CANCER THERAPY: Different forms of therapy- Chemotherapy- Radiation Therapy- Detection of Cancers- Prediction of aggressiveness of Cancer- Advances in Cancer detection- Bioinformatics and Cancer. Role of machine learning and deep learning in cancer research. Cancer screening and detection via AI integration. | 08 |
Text Books
- King R. J. B., “Cancer Biology”, Addison Wesley Longmann Ltd, U.K., 1996.
- Ruddon R.W., “Cancer Biology”, Oxford University Press, Oxford, 1995.
- Maly B.W.J., “Virology a practical approach”, IRL press, Oxford, 1987.
- Dunmock N.J. and Primrose S.B., “Introduction to modern Virology”, Well Scientific Publications, Oxford, 1988.
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