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AKTU Bioinformatics II Lab (BBT653) Syllabus PDF – B.Tech 3rd Year
Bioinformatics II Lab BBT653
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Official AKTU syllabus of Bioinformatics II Lab (BBT653) for B.Tech 3rd Year – 1 credits, L-T-P 0-0-2. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Bioinformatics II Lab
Download PDFBBT653 · 1 credits · L-T-P 0-0-2
EXAM DURATION: 2 Hours SEMESTER: VI (EVEN) L: T: P :: 0 : 0 : 2 CREDITS: 1 PREREQUISITE: Bioinformatics II theory course
Course Objectives
- To introduce the fundamental principles of bioinformatics
- To make them correlate theory and practical processes through experimentation. Course Outcomes (Six): After successful completion of this course, the students will be able to:
- Understand the basic software and tools used in structure prediction of biomolecules
- Conduct experimental procedure for Ramachandran plot and its analysis
- Construct and analyse of restriction maps, QSAR model and homology model
- Identify and structurally modify a natural product, to design a compound with the desired properties and to assess its therapeutic effects, theoretically.
- Enhance their practical knowledge and thus their employability
- Construction of primer for PCR. CO-PO Mapping (1 to 3 scale)
| CO/PO | PO-1 | PO-2 | PO-3 | PO-4 PO-5 PO-6 PO-7 PO-8 PO-9 PO- 10 PO- 11 PO- 12 |
| CO-1 | 2 | 3 | 2 | 1 |
| CO-2 | 2 | 1 | 3 | 1 2 1 |
| CO-3 | 2 | 1 | ||
| CO-4 | 2 | 3 | 1 | 2 1 |
| CO-5 | 2 | 3 | 2 | 1 |
| CO-6 | 2 | 3 | 2 | 1 |
Reference Books
| S. No. | Name Of Authors/Books/Publishers | Year of Publication/ Reprint |
| 1 | Alphey L. DNA sequencing: from experimental methods to bioinformatics. BIOS scientific publishers Ltd; 1997. | 1997 |
| 2 | Iftekhar M, Ghalib MR. Bioinformatics Practical Manual | 2015 |
| 3 | Karthikeyan M, Vyas R. Practical chemoinformatics. Springer; 2014 May 6 | 2014 |
| 4 | Brown FK. Chemoinformatics: what is it and how does it impact drug discovery. Annual reports in medicinal chemistry. 1998 Jan 1;33:375-84 | 1998 |
Course Details
| S. No | List of Experiments |
| 1 | Identification of Distantly related homologous sequences of a given query protein sequence using PSI-BLAST |
| 2 | Construct Phylogenetic tree of five evolutionary related protein/nucleotide sequences |
| 3 | Prediction of secondary structure of RNA using any web server. |
| 4 | Construction and analysis of Ramachandran Plot using any suitable web server |
| 5 | Align two homologous protein structure and calculation the RMSD for the superposition result |
| 6 | Comparative assessment of best available tools for genome annotation |
| 7 | Construction of restriction maps for various vectors used in genetic engineering using tool “NEB cutter”. |
| 8 | Primer Design: Construct primers for the given DNA sequence using any suitable web based tool |
| 9 | Generate 2D QSAR model of a set of legend descriptor data |
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