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AKTU Systemic Pharmacology I (Theory) (BP405T) Syllabus PDF – B.Pharm 4th Semester
Systemic Pharmacology I (Theory) BP405T
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Official AKTU syllabus of Systemic Pharmacology I (Theory) (BP405T) for B.Pharm 4th Semester – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Systemic Pharmacology I (Theory)
Download PDFBP405T · 3 credits · L-T-P 3-0-0
Course Objectives
- Develop a comprehensive understanding of neurohumoral transmission, neurotransmitters, and the organization and function of the autonomic nervous system.
- Provide knowledge of the classification, mechanisms of action, and pharmacological effects of various classes of drugs.
- Explain the pharmacology of drugs acting on the peripheral nervous system, cardiovascular system, and urinary system.
- Describe the physiological roles of autacoids and the pharmacology of drugs used in the management of pulmonary diseases and related disorders.
- Familiarize students with the pharmacology of drugs acting on the immune system, hematopoietic system, and blood, and relate pharmacological principles to clinical conditions through case-based learning.
Course Outcomes
| CO | Upon successful completion of this course, the students will be able to |
| No. | |
| 1 | Explain the classification of neurotransmitters and describe neurohumoral transmission, including the organization, function, and pharmacological modulation of the autonomic nervous system. |
| 2 | Classify and explain the mechanisms of action, pharmacological effects, and therapeutic uses of drugs used in cardiovascular disorders such as heart failure, arrhythmias, hypertension, angina, and lipid disorders. |
| 3 | Describe the pharmacology and therapeutic uses of drugs acting on blood and kidney, including anticoagulants, antiplatelet agents, hematinics, and diuretics. |
| 4 | Explain the physiological roles of autacoids and analyze the pharmacology of drugs that modulate autacoid pathways, including antihistamines, antimigraine agents, NSAIDs, and antirheumatic drugs. |
| 5 | Evaluate the mechanisms of action, therapeutic uses, and adverse effects of drugs acting on the respiratory and immune systems. |
Course Content
| Unit | Topics | No. of |
|---|---|---|
| I | Pharmacology of drugs acting on the peripheral nervous system a) Organization and functions of PNS. b) Neurohumoral transmission, co-transmission. Neurotransmitters and their receptors, including non-adrenergic and non-cholinergic (NANC) neurotransmitters. c) Parasympathomimetic and Parasympatholytic drugs. d) Sympathomimetic and sympatholytic drugs. e) Skeletal muscle relaxants (peripheral and central). f) Drugs used in the treatment of myasthenia gravis and glaucoma | 10 Hours |
| II | Pharmacology of drugs acting on the cardiovascular system a) Introduction to cardiovascular hemodynamic and cardiac electrophysiology. b) Drugs used in congestive cardiac failure. c) Anti-arrhythmic drugs. d) Anti-anginal and newer anti-ischemic drugs. e) Anti-hypertensive drugs. f) Shock, types of shocks and drugs used in their management. g) Stroke, types of strokes and drugs used in their management | 10 Hours |
| III | Pharmacology of drugs acting on blood and kidney 1. Pharmacology of drugs acting on blood a) Anti-platelet agents b) Coagulants and anticoagulants. c) Fibrinolytics and Plasma expanders. d) Haematinics. e) Anti-hyperlipidaemic drugs. 2. Pharmacology of drugs acting on kidney a) Diuretics. b) Anti-diuretics. | 10 Hours |
| IV | Pharmacology of autacoids and related drugs a) Introduction to autacoids and their classification. Therapeutic significance of important agonists and antagonists of prostaglandins, thromboxane, leukotrienes, angiotensin, bradykinin and substance P. b) Histamine and antihistamines. c) 5-HT, its agonists and antagonists, drugs used in migraine. d) Non-steroidal anti-inflammatory drugs, antipyretics and analgesics. e) Anti-gout and Antirheumatic drugs including Disease Modifying Antirheumatic Drugs (DMARDs). | 9 Hours |
| V | i) Pharmacology of Drugs acting on respiratory system a) Drugs used in the treatment of bronchial asthma and COPD. b) Definitions, classification and therapeutic uses of nasal decongestants, | 6 Hours |
mucolytics, expectorants and antitussives.
- Respiratory stimulants. ii) Pharmacology of Drugs acting on immune system Mechanism of action, adverse effects and therapeutic uses of important classes of immune stimulants and immunosuppressants.
Recommended References
- Brunton, L., Hilal-Dandan, R. and Knollmann, B. Pharmacological Basis of Therapeutics. McGraw-Hill Education.
- Craig, C. R. and Stitzel, R. E. Modern Pharmacology with Clinical Applications. Lippincott Williams & Wilkins.
- DiPiro, J. T., Talbert, R. L., Yee, G. C. and Matzke, G. R. Pharmacotherapy: A Pathophysiologic Approach. McGraw-Hill Education.
- Katzung, B. G. and Trevor, A. J. Basic and Clinical Pharmacology. McGraw-Hill Education.
- Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J. and Henderson, G. Rang and Elsevier.
- Tripathi, K. D. Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers.
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