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AKTU Systemic Pharmacology II (Theory) (BP506T) Syllabus PDF – B.Pharm 5th Semester

Systemic Pharmacology II (Theory) BP506T

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Official AKTU syllabus of Systemic Pharmacology II (Theory) (BP506T) for B.Pharm 5th Semester – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.

Syllabus — Systemic Pharmacology II (Theory)

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BP506T · 3 credits · L-T-P 3-0-0

Course Objectives

  1. Understand the neurohumoral transmission in the central nervous system and the role of neurotransmitters and their modulators in CNS disorders.
  2. Learn the pharmacology of drugs used in pathological conditions of CNS, GIT, and endocrine system.
  3. Familiarize learners with concepts of drug abuse, addiction, dependence, tolerance, and their management.
  4. Impart comprehensive knowledge of chemotherapeutic agents including anticancer drugs.
  5. Introduce the principles of rational use of chemotherapeutic agents.

Course Outcomes

COUpon successful completion of this course, the students will be able to
No.
1Identify the role of neurotransmitters in CNS diseases and explain pharmacology of drugs acting on central neurotransmission.
2Apply principles of chemotherapy to explain mechanisms and uses of chemotherapeutic agents.
3Recall pharmacology of hormones and drugs used in endocrine disorders.
4Describe mechanisms and therapeutic uses of drugs acting on the gastrointestinal tract.
5Recognize issues related to drug abuse, addiction, and dependence and their management.

Course Content

UnitTopicsNo. of
IPharmacology of Drugs Acting on Central Nervous System Neurohumoral transmission in the CNS; physiological roles of GABA, glutamate, glycine, serotonin, and dopamine. a. General anesthetics, pre-anaesthetic medications, and local anaesthetic agents b. Sedative hypnotics c. Alcohol and disulfiram d. Opioids, opiate analgesics, and antagonists e. Drugs used in epilepsy10 hours
IIPharmacology of Drugs Used in Psychiatry a. Antipsychotics, antidepressants, anti-anxiety drugs, mood stabilizers, CNS stimulants, and hallucinogens b. Substance abuse, drug addiction, and general principles of de-addiction07 hours
IIIChemotherapy i) Introduction a. Definitions of chemotherapy, chemotherapeutic index, antibiotics, and antimicrobial agents b. Concept of selective targeting in chemotherapy c. Classification of antimicrobial agents based on mechanism of action d. Concept of superinfection, chemoprophylaxis, and combined use of antibiotics e. Antimicrobial resistance: causes, mechanisms, and preventive measures ii) Antimicrobial Agents Classification, mechanism of action, adverse drug reactions, and therapeutic uses of: Sulphonamides and cotrimoxazole Fluoroquinolones Penicillins and cephalosporins Macrolides and tetracyclines Linezolid Carbapenems and monobactams Chloramphenicol and aminoglycosides iii) Chemotherapy of Diseases Drugs used in the treatment of: Fungal infections Viral infections14 hours

Helminthiasis Urinary tract infections Tuberculosis Leprosy Malaria Amoebiasis Neoplastic diseases

IVPharmacology of Drugs Acting on Endocrine System a. Introduction to basic concepts of endocrinology b. Thyroid and antithyroid agents c. Parathormone, calcitonin, and vitamin D d. Insulin and oral hypoglycaemic agents e. ACTH and corticosteroids f. Oral contraceptives g. Drugs acting on the uterus h. PCOD10 hours
VDrugs Acting on Gastrointestinal Tract a. Drugs used in peptic ulcer b. Drugs used for constipation and diarrhoea c. Emetics and anti-emetics d. Digestants, carminatives, appetizers, and anorectics definitions and examples04 hours

Recommended References

  1. Brunton, L., Hilal-Dandan, R. and Knollmann, B. Pharmacological Basis of Therapeutics. McGraw-Hill Education.
  2. Craig, C. R. and Stitzel, R. E. Modern Pharmacology with Clinical Applications. Lippincott Williams & Wilkins.
  3. DiPiro, J. T., Talbert, R. L., Yee, G. C. and Matzke, G. R. Pharmacotherapy: A Pathophysiologic Approach. McGraw-Hill Education.
  4. Katzung, B. G. and Trevor, A. J. Basic and Clinical Pharmacology. McGraw-Hill Education.
  5. Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J. and Henderson, G. Rang and Elsevier.
  6. Tripathi, K. D. Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers.

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