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AKTU Biomedicinal Chemistry (Practical) (BP507P) Syllabus PDF – B.Pharm 5th Semester
Biomedicinal Chemistry (Practical) BP507P
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Official AKTU syllabus of Biomedicinal Chemistry (Practical) (BP507P) for B.Pharm 5th Semester – 2 credits, L-T-P 0-0-4. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Biomedicinal Chemistry (Practical)
Download PDFBP507P · 2 credits · L-T-P 0-0-4
Course Objectives
- Comprehend the fundamental principles of drug synthesis and apply them to the preparation of selected drug molecules and intermediates.
- Develop practical skills in performing laboratory techniques for the synthesis of organic compounds, including the use of microwave irradiation.
- Understand and apply the principles of drug assay to quantitatively analyze the purity and concentration of given drug samples.
- Learn and utilize computational tools to predict physicochemical and ADME properties of drug molecules.
- Apply molecular docking techniques to predict drug-target interactions.
Course Outcomes
| CO | Upon successful completion of this course, the students will be able to: |
| No. | |
| 1 | Successfully synthesize specified drug molecules and intermediates in the laboratory. |
| 2 | Demonstrate competence in using microwave irradiation for efficient chemical synthesis. |
| 3 | Accurately perform drug assays to determine the concentration and purity of drug samples. |
| 4 | Analyze physicochemical and ADME properties of drug candidates using computational tools. |
| 5 | Conduct and interpret molecular docking studies to understand drug-receptor binding. |
Course Content
List of practical
- Preparation of Drugs / Intermediates (Any 4) 7-Hydroxy-4-methyl coumarin Thiobarbituric acid 2,3-Diphenylquinoxaline Sulphanilamide Triphenyl imidazole Perform synthesis of intermediate/drug using microwave irradiation or green chemistry techniques.
- Assay of Drugs (Any 4) Sulpha drugs Metronidazole Isoniazid Phenobarbitone Benzyl penicillin Chloroquine
- Drug Design & Computational Tools (Any 4) Calculate physicochemical and ADME properties using Swiss ADME (e.g. logP, molecular weight, H-bond donors/acceptors) Perform basic molecular docking studies using any of open-source academic tools.
Recommended References
- Abraham, D. J. and Griffin, J. L. Wiley.
- Finar, I. L. Organic Chemistry. Pearson Education.
- Furniss, B. S., Hannaford, A. J., Smith, P. W. G. and Tatchell, A. R. Practical Organic Chemistry. Pearson Education.
- Lednicer, D. The Organic Chemistry of Drug Synthesis. Wiley.
- Patrick, G. L. An Introduction to Medicinal Chemistry. Oxford University Press.
- Remington. The Science and Practice of Pharmacy. Pharmaceutical Press.
- Williams, D. A., Lemke, T. L. and Roche, V. F. Chemistry. Lippincott Williams & Wilkins.
- Wilson, C. O., Beale, J. M. and Block, J. H. Medicinal and Pharmaceutical Chemistry. Lippincott Williams & Wilkins.
- Indian Pharmacopoeia. Indian Pharmacopoeia Commission.
- Brown, N. Artificial Intelligence in Drug Discovery. Cambridge: Royal Society of Chemistry.
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