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AKTU Principles of Molecular Genetics (BBI401) Syllabus PDF – B.Tech 2nd Year
Principles of Molecular Genetics BBI401
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Official AKTU syllabus of Principles of Molecular Genetics (BBI401) for B.Tech 2nd Year – 4 credits, L-T-P 3-1-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Principles of Molecular Genetics
Download PDFBBI401 · 4 credits · L-T-P 3-1-0
Course Outcomes
Course Outcomes
| CO1 | Understand the fundamental Structure of DNA | K2 |
| CO2 | Discuss the process of DNA replication & different repair mechanisms. | K2 |
| CO3 | Discuss the process of Gene expression and its regulation, DNA repair and Comprehend mutation and its causes | K3 |
| CO4 | Understand the basis of inheritance and chromosome organization | K2 |
| CO5 | Discuss linkage and crossing over mechanism of chromosome | K3 |
Course Content
L-T-P: 3-1-0
| Unit | Topic | Proposed Lecture |
|---|---|---|
| I | STRUCTURE OF NUCLEIC ACID :Structure of DNA - Different forms of DNA and RNA – Identification of DNA as genetic material by Griffith–Avery, McLeod and McCarty-Frankel and Singer- Hershey and ChaseMesselson and Stahl experiment. | 08 |
| II | DNA REPLICATION AND MUTATION : Semi-Conservative replication - replication of DNA in Eukaryotes - molecular basis of Mutation- classification of mutation, DNA Repair mechanism | 08 |
| III | GENE EXPRESSION AND REGULATION: Genetic code – transcription- prokaryotes and Eukaryotes- Post transcriptional modification - Translation in prokaryotes and Eukaryotes - Post translational modification-Gene Regulation- Lac operon model | 08 |
| IV | MENDELIAN GENETICS – monohybrid – dihybrid inheritance- multiple alleles- structure and organization of chromosome in prokaryote and Eukaryotes. | 08 |
| V | CROSSING OVER AND LINKAGE: Linkage –types of linkage-crossing over and their types Recombination mapping by two point and three point text cross mapping in bacteria. | 08 |
Text Books
- Genetics a conceptual approach, 2nd Edition Benjamin A. Pierc WH freeman and, company, New York
- Advance Genetics by G.S. Miglani, Narosa Publishing House.
- Albert B, Bray Denis et al.: Molecular Biology of The Cell, latest ed.
- Watson, Hopkins, Roberts et al. Molecular Biology of the Gene, 4 th ed.
- Genetics-Strickberger, 2nd.
- Baltimore-Molecular Biology of the Cell
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