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AKTU Computational Biology Lab (BBI353) Syllabus PDF – B.Tech 2nd Year
Computational Biology Lab BBI353
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- Semester 3
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Official AKTU syllabus of Computational Biology Lab (BBI353) for B.Tech 2nd Year – 1 credits, L-T-P 0-0-2. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Computational Biology Lab
Download PDFBBI353 · 1 credits · L-T-P 0-0-2
Course Outcomes
At the end of course, the student will be able to
| CO 1 | Identify and describe different types of biological databases and their purposes. | K1 |
| CO 2 | Retrieve sequences from databases and perform similarity searches for nucleotide and protein data, study GenBank flat file | K3 |
| CO 3 | Analyze protein properties and identify homologous sequences to infer functional/evolutionary relationships. | K4 |
| CO 4 | Perform multiple sequence alignment and apply dynamic programming methods for sequence comparison. | K4 |
| CO 5 | Evaluate and implement gene prediction methods to identify coding regions in genomic sequences. | K5 |
Course Content
List of Experiments
- Knowledge of different biological database
- Protein and gene sequence databases (NCBI, DDBJ, EMBL, SWISS PROT, PIR)
- Structured at a bases (MMDB, PDB, CATH, SCOP)
- Pathway Databases (KEGG, BRENDA, METACYC)
- Bibliographic database (PUBMED, MEDLINE)
- Sequence retrieval from biological database
- To retrieve nucleotide sequences from GenBank in flat file format.
- To identify and analyze various fields (LOCUS, DEFINITION, ACCESSION, FEATURES, ORIGIN) in a GenBank flat file.
- Retrieve a protein structure (PDB file) from the Protein Data Bank (PDB) and visualize it using PyMOL, Chimera, or Jmol.
- Identify alpha-helices, beta-sheets, and active sites.
- Sequence similarity searching of nucleotide and protein sequences
- Finding homologous sequences
- Multiples Sequence alignment
- Dynamic programming method-local and global alignment
- Gene prediction methods Note: The instructor may add/delete/modify/tune experiments DR. A.P.J. ABDUL KALAM TECHNICAL U NIVERSITY, LUCKNOW, UTTAR PRADESH B. TECH (BIOINFORMATICS) FOURTH SEMESTER (DETAILED SYLLABUS)
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