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AKTU Physical Pharmaceutics (Practical) (BP211P) Syllabus PDF – B.Pharm 2nd Semester
Physical Pharmaceutics (Practical) BP211P
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Official AKTU syllabus of Physical Pharmaceutics (Practical) (BP211P) for B.Pharm 2nd Semester – 1 credits, L-T-P 0-0-3. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Physical Pharmaceutics (Practical)
Download PDFBP211P · 1 credits · L-T-P 0-0-3
Course Objectives
- Introduce basic laboratory techniques for determining physicochemical properties such as surface tension, viscosity, and density in pharmaceutical systems.
- Develop understanding of interfacial phenomena and surfactant behavior, including micelles, critical micellar concentration (CMC), and HLB in formulation design.
- Train students in evaluating disperse systems through sedimentation studies and the effect of suspending agents.
- Provide practical experience in powder characterization, including particle size distribution, density, flow properties, porosity, and the role of glidants.
- Develop skills in determining solubility, partition coefficient, buffer capacity, and related equilibria relevant to drug formulation.
Course Outcomes
| CO | Upon successful completion of this course, the students will be able to: |
| No. | |
| 1 | Demonstrate practical knowledge of principles and procedures involved in measuring surface tension, viscosity, density, and related physical properties using standard laboratory apparatus. |
| 2 | Determine and interpret surfactant-related parameters such as CMC and HLB and explain their significance in formulation stability and performance. |
| 3 | Conduct experiments and analyze results related to sedimentation volume and evaluate the influence of type and concentration of suspending agents on dispersion stability. |
| 4 | Evaluate micromeritic and flow properties of powders by determining particle size repose, true density, and porosity, and interpret the effect of glidants. |
| 5 | Perform and assess experiments on solubility, partition coefficient, critical solution temperature, adsorption studies, and buffer capacity, and apply findings to formulation decisions. |
Course Content
List of practical (Minimum 12 experiments must be performed)
- Determination of surface tension of given liquids by drop count method and drop weight method.
- Determination of critical micellar concentration (CMC) of surfactants. 3. viscometer.
- Determination of HLB value of a surfactant.
- Calculation of isotonicity by different methods (Sodium Chloride Equivalent Method).
- Determination of particle size and particle size distribution using sieving method.
- Determination of particle size and particle size distribution using microscopic method.
- Determination of densities and derived properties of powders (bulk density, tapped
- Determination of angle of repose and influence of glidants on angle of repose.
- Determination of solubility of a drug at different pH/buffer systems at room temperature.
- Determination of partition coefficient of a drug in n-octanol and water system.
- Determination of partition coefficient of a drug in benzene and water system.
- Determination of critical solution temperature and composition of phenol water system.
- Determination of specific surface area of charcoal by adsorption of acetic acid on activated charcoal.
- Determination of buffer capacity at various stages of titration of a weak acid against a strong base and determination of pKa. Note: Compare the values of various physicochemical properties with marketed formulations wherever possible.
Recommended References
- Sinko, P. J. Lippincott Williams & Wilkins.
- Aulton, M. E. and Taylor, K. M. G. Manufacture of Medicines. Elsevier.
- Lachman, L., Lieberman, H. A. and Kanig, J. L. The Theory and Practice of Industrial Pharmacy. CBS Publishers & Distributors.
- Allen, L. V., Popovich, N. G. and Ansel, H. C. and Drug Delivery Systems. Lippincott Williams & Wilkins.
- Cooper, S. J. and Gunn, C. CBS Publishers & Distributors.
| Course Code* | Course Title* | Course Type |
| BP212P SEC1 | Communication Skills | Elective |
| BP212P SEC2 | Mental Well-Being, Stress & Conflict Management | |
| BP212P SEC3 | Fundamentals of Computer Operations | |
| Credit | Hours Per Week (L-T-P) | Max. Hours |
| L | T | P |
| 1 | -- | 2 30 |
| Maximum Marks | SE | ESE |
| 50 | 20 | 30 |
* Only 1 elective course shall be selected The syllabi for elective subjects are given in the APPENDIX Semester III**
| Course Code | Name of the Course | No. of hours/week (L/P) | Continuous Mode (Marks) | Sessional Exam (Marks) | Sessional Duration | Internal Total | End Semester Marks | Exam Duration | Total Marks Credit points |
| BP301T | Introduction to Machine Learning in Pharmaceutical Sciences (Theory) | 2 | 10 | 1 Hr | 20 | 30 | 1.5 Hr | 50 | 2 |
| BP302T | Environmental Science (Theory) | 1 | 10 | 1 Hr | 20 | 30 | 1.5 Hr | 50 | 1 |
| BP303T | Ethics and Universal Human Values (Theory) | 1 | 10 | 1 Hr | 20 | 30 | 1.5 Hr | 50 | 1 |
| BP304T | General Pharmacology (Theory) | 3 | 15 | 1 Hr | 30 | 45 | 2 Hr | 75 | 3 |
| BP305T | Heterocyclic Compounds and Stereochemistry (Theory) | 3 | 15 | 1 Hr | 30 | 45 | 2 Hr | 75 | 3 |
| BP306T | Pharmaceutical Dosage Forms I (Theory) | 3 | 15 | 1 Hr | 30 | 45 | 2 Hr | 75 | 3 |
| BP307T | Pharmaceutical Engineering (Theory) | 3 | 15 | 1 Hr | 30 | 45 | 2 Hr | 75 | 3 |
| BP308T | Pharmaceutical Microbiology (Theory) | 3 | 15 | 1 Hr | 30 | 45 | 2 Hr | 75 | 3 |
| BP309P | General Pharmacology (Practical) | 4 | 10 | 4 Hr | 20 | 30 | 4 Hr | 50 | 2 |
| BP310P | Heterocyclic Compounds and Stereochemistry (Practical) | 4 | 10 | 4 Hr | 20 | 30 | 4 Hr | 50 | 2 |
| BP311P | Pharmaceutical Dosage Forms I (Practical) | 3 | 10 | 3 Hr | 20 | 30 | 3 Hr | 50 | 1 |
| BP312P | AEC* – Elective 2 (Practical) | 2 | 10 | 3 Hr | 20 | 30 | 3 Hr | 50 | 1 |
| Total | 32 | 145 | 22 Hr | 360 | 435 | 28.5 Hr | 725 | 25 |
* Only 1 elective course shall be selected The syllabi for elective subjects are given in the APPENDIX **The lateral entry students taking admission directly to second year shall compulsorily appear for and pass the subjects, Healthcare Psychology and Communication Skills (Theory and Practical) and Basics of Python Programming for Pharmaceutical Sciences (Theory) during the Third Semester.
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