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AKTU Virology (BOE088) Syllabus PDF – B.Tech Open Elective
Virology BOE088
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Official AKTU syllabus of Virology (BOE088) for B.Tech Open Elective – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Virology
Download PDFBOE088 · 3 credits · L-T-P 3-0-0
Course Content
L-T-P: 3-1-0
| Unit | Topic | Proposed Lecture |
|---|---|---|
| I | General Concepts: Virus history, Diversity, shapes, sizes and components of genomes. Isolation and purification of viruses and components. | 08 |
| II | Consequences of virus infection to animals and human. Viral infection: affect on host macromolecules. Viral infection: establishment of the antiviral state. Viruses counter attack mechanisms. Viral diagnostic techniques: Rapid Antigen testing, RTPCR. | 08 |
| III | Classification of viruses and nomenclatures. +strand RNA viruses- Picorna viruses. Flavi viruses- West Nile virus and Dengue virus. Corona viruses- SARS pathogens. Small DNA viruses: parvo- and polyoma viruses. Large DNA viruses: Herpes-adeno-, and poxviruses. Miscellaneous viruses. | 08 |
| IV | –ve strand RNA viruses Paramyxo viruses. Orthomyxo viruses: Influenza pathogenesis and Bird flu. Rhabdo viruses: Rabies pathogenesis.. dsRNA viruses- Reo viruses. Retroviruses: structure, classification, life cycle; reverse transcription. Retroviruses: HIV, viral pathogenesis and AIDS. | 08 |
| V | Antivirals and viral vaccines Viral Vaccines Conventional vaccines- killed and attenuated, modern vaccinesrecombinant proteins, subunits, DNA vaccines, peptides, immunemodulators (cytokines), vaccine delivery and adjuvants, large scale manufacturing- QA/QC issues. Antivirals Interferons, designing and screening of antivirals, mechanism of action, antiviral libraries, antiretrovirals- mechanism of action and drug resistance. Modern approaches of virus control Anti-sense RNA, siRNA, ribozymes. | 08 |
Reference Books
- Antiviral Agents, Vaccines and immunotherapies. Stephen K. Tyring. ISBN 9780367393748 CRC
- Basic Virology – Edward K Wanger. Blackwell Publication
- Fundamentals of molecular virology – Acheson and Nicholas H,2011 4. Principles of Virology 2nd edition by S.J.Flint, L.W.Enquist, R.M.Krug,V.R. Racaniello, and A.M.Skalka ASM Press
- Medical Virology 4th edition by David O.White and Frank J. Fenner. Academic Press.
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