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AKTU Industrial Biotechnology (BBT074) Syllabus PDF – B.Tech 4th Year
Industrial Biotechnology BBT074
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Official AKTU syllabus of Industrial Biotechnology (BBT074) for B.Tech 4th Year – 3 credits, L-T-P 3-0-0. Read the unit-wise course content, course outcomes, evaluation pattern and recommended books online, or download the PDF.
Syllabus — Industrial Biotechnology
Download PDFBBT074 · 3 credits · L-T-P 3-0-0
Course Objectives
To provide the knowledge of Industrial Biotechnology. To understand the use of living cells such as bacteria, yeast, algae or component of cells like enzymes, plants and animals to generate industrial products and processes. To study techniques for genetic improvement of micro-organisms to improve yield of bioproducts. To provide the knowledge of microbial production of pharmaceuticals. To provide knowledge about biofuels. COURSE OUTCOME: After successful completion of the course the students will be able to:
| CO1 | Understand the role of industrial biotechnology in improving microbial cells as factories | Understand |
| CO2 | Understand the different types of bioreactors and the production aspects of commodity chemicals, pharmaceuticals and fine chemicals. | Understand & Analyze |
| CO3 | Apply knowledge of microorganisms in commercial production of flavours, fragrance, and microbial pigment in textile and industry. | Create |
| CO4 | Apply the process for commercial production of enzyme. | Apply |
| CO5 | Understand the concept of biofuels and the process of Microbial Enhanced Oil Recovery and Microbial Leaching. | Understand, Analyze & Create |
Course Content
| Unit | CONTENT | LECTURE |
|---|---|---|
| I. | Introduction to Industrial Biotechnology: Introduction and scope of industrial biotechnology, historical overview of industrial fermentation processes, unit operations involved, products and market economics. Microorganisms: Isolation of industrially important microorganisms, isolation methods utilizing selection of desired characteristics, methods not utilizing selection of desired characteristics, preservation and maintenance of microorganisms, improvement of industrial microorganisms for overproduction of primary and secondary metabolites, improvement of strains by modifying properties other than the yield of products. | 12 |
| II. | Raw materials for fermentation process: Media requirements for fermentation processes, simple and complex media, medium formulation, carbon sources, nitrogen sources, minerals, vitamins and other nutrients, precursor, induces, chelator, growth factors, antifoams. | 8 |
| III. | Commercially important products: Alcohol, alcoholic beverages beer and wines etc, beneficial soil microorganisms. bio pesticides, biofertilizer, single cell proteins, baker’s yeast, high fructose corn syrup, organic acids, acetone, butanol etc., biopreservatives (Nisin), cheese, biopolymers (xanthan gum, PHB etc), Bioflavours and biopigments; microbial production of flavours and fragrances; microbial pigments in textile and food industry. | 10 |
| IV. | Microbial production of pharmaceuticals and other bioproducts: Antibiotics, vitamins, enzyme and proteins, enzyme inhibitors and specialty chemicals; Transformation of nonsteroidal compounds, antibiotics, genetic engineering of microorganisms for production of nonribosomal peptides (NRPS) and polyketides (PKS), anticancer drugs. | 8 |
| V. | Bioreactors, Production of cell biomass and Bioenergy: Different type of Bioreactors and Bioreactor design, Production of ethanol, acetone, butanol, citric acid, dextran and amino acids, fuel from biomass, production and economics of biofuels, biogas, bio-refineries, Microbial Enhanced Oil Recovery (MEOR). | 10 |
| Total lectures | 48 |
Reference Books
| S.No | NAME OF AUTHORS/BOOKS/PUBLISHERS | YEAR OF PUBLICATION |
| 1. | Reed G, “Prescott and Dunn’s Industrial Microbiology” CBS publishers and distributors, New Delhi (1987). , | 1987 |
| 2. | P.F. Stansbury and A. Whitaker, Principles of Fermentation Technology: An Introduction to Current Concepts, Pergamon Press 1993 | 1993 |
| 3. | Glazer AN, Nikaido H : Microbial Biotechnology: Fundamentals of Applied Microbiology. 2007 | 2007 |
| 4. | Malden MA: Industrial Microbiology: An introduction; Blackwell Science 2001 | 2001 |
| 5. | Casida L E, “Industrial Microbiology” , New Age International Publishers Ltd. | 2003 |
| 6. | Mansi E M T EL, Bryce C F A, “Fermentation Microbiology and Biotechnology”. Ane Books Publishers and Distributors | 2003 |
| 7. | Shuler M L, Kargi F, “ Bioprocess Engineering- Basic Concepts” , 2nd ed, Prentice Hall of India Ltd. | 2002 |
| 8. | C. Vogel and C.L. Tadaro, Fermentation and Biochemical Engineering Handbook: Principles, Process, Design and Equipment, Noyes Publications | 1996 |
| 9. | Wulf Cruger and Anneliese Crueger, Biotechnology: A Textbook of Industrial Microbiology, Panima Publishing Corporation | 2003 |
| 10. | Crueger W and Crueger A, “Biotechnology: A Text book of Industrial Microbiology” Sinouer Associate, Inc. Sunderland MA, USA | 1990 |
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